Relevant Publications
Nature 2009
Stanton, B., Peng, L., Maloof, N., Nakai, K., Wang, X., Duffner, J., Taveras, K., Hyman, J., Lee, S., Koehler, A., Chen, J., Fox, J., Mandinova, A., Schreiber, S. A small molecule that binds Hedgehog and blocks its signaling in human cells. Nature Chemical Biology, 2009.
ChemSocRev 2008
Vegas, A., Fuller, J., and Koehler, A. Small-molecule microarrays as tools in ligand discovery. Chemical Society Review, 2008.
Angewandte Chemie 2007
Vegas, A., Bradner, J., Tang, W., McPherson, O., Greenberg, E., Koehler, A., Schreiber, S. Fluorous-Based Small-Molecule Microarrays for the Discovery of Histone Deacetylase Inhibitors. Angewandte Chemie International Edition, 2007.
Nature Protocols 2006
Bradner, J., McPherson, O., Koehler, A. A method for the covalent capture and screening of diverse small molecules in a microarray format. Nature Protocols, 2006.
Chemistry & Biology 2006
Bradner, J., McPherson, O., Mazitschek, R., Barnes-Seeman, D., Shen, J., Dhaliwal, J., Stevenson, K., Duffner, J., Park, S., Neuberg, D., Nghiem, P., Schreiber, S., Koehler, A. A Robust Small-Molecule Microarray Platform for Screening Cell Lysates. Chemistry and Biology, 2006.
JACS 2003
Koehler, A., Shamji, A., Schreiber, S. Discovery of an Inhibitor of a Transcription Factor Using Small Molecule Microarrays and Diversity-Oriented Synthesis. Journal of the American Chemical Society, 2003.
Nature 2002
Kuruvilla, F., Shamji, A., Sternson, S., Hergenrother, P., Schreiber, S. Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays. Nature, 2002.
JACS 1999
MacBeath, G., Koehler, A., Schreiber, S. Printing Small Molecules as Microarrays and Detecting Protein−Ligand Interactions en Masse. Journal of the American Chemical Society, 1999.